Alprostadil
| Product dosage: 500mcg | |||
|---|---|---|---|
| Package (num) | Per injection | Price | Buy |
| 1 | 300.00 $
Best per injection | 300.00 $ (0%) | 🛒 Add to cart |
Alprostadil-–-Advanced-Vasodilator-for-Erectile-Dy
Introduction
Alprostadil is a synthetic prostaglandin E1 (PGE1) analog widely recognized for its potent vasodilatory effects. Clinically approved for the treatment of erectile dysfunction (ED) and certain cardiovascular conditions, Alprostadil enhances blood flow through smooth muscle relaxation, ensuring optimal therapeutic outcomes. Available in multiple formulations—including intracavernosal injections, urethral suppositories, and topical creams—this medication offers flexibility, efficacy, and rapid onset of action.
Backed by extensive clinical research, Alprostadil stands as a first-line treatment for patients unresponsive to oral PDE5 inhibitors (e.g., sildenafil, tadalafil). Its precision-engineered molecular structure ensures high bioavailability and minimal systemic side effects, making it a preferred choice among healthcare providers.
Technical Specifications
1. Pharmacological Profile
- Active Ingredient: Alprostadil (Prostaglandin E1)
- Mechanism of Action: Binds to prostaglandin receptors, activating adenylate cyclase → ↑ cAMP → smooth muscle relaxation → vasodilation
- Bioavailability:
- Intracavernosal: ~95%
- Intraurethral: ~30-40%
- Onset of Action:
- Injection: 5–15 minutes
- Urethral pellet: 10–30 minutes
- Half-Life: 5–10 minutes (systemic)
2. Formulations & Dosages
| Formulation | Available Strengths | Storage Conditions |
|---|---|---|
| Injection (Caverject, Edex) | 5 mcg, 10 mcg, 20 mcg, 40 mcg | 2–8°C (refrigerated) |
| Urethral Pellet (MUSE) | 125 mcg, 250 mcg, 500 mcg, 1000 mcg | Room temperature (<25°C) |
| Topical Cream (Vitaros) | 200 mcg/g, 300 mcg/g | Below 30°C |
3. Compatibility & Safety
- Contraindications: Priapism risk, sickle cell anemia, penile deformities
- Drug Interactions: Anticoagulants (↑ bleeding risk), antihypertensives (↑ hypotension)
- Pregnancy Category: C (not for use in women)
Key Advantages of Alprostadil
✅ High Efficacy Rate – 70–80% success in ED patients, including diabetics and post-prostatectomy cases.
✅ Rapid Action – Faster results than oral PDE5 inhibitors (works even with low nitric oxide levels).
✅ Flexible Administration – Multiple delivery methods for patient convenience.
✅ Minimal Systemic Effects – Localized action reduces headaches, flushing, and dyspepsia.
✅ Proven Safety – Decades of clinical use with well-documented tolerability.
Performance Rating: ⭐⭐⭐⭐⭐ (5/5 Stars)
- Effectiveness: ★★★★★
- Ease of Use: ★★★★☆ (injection requires training)
- Side Effect Profile: ★★★★☆ (low risk of priapism/pain)
- Cost-Effectiveness: ★★★☆☆ (higher than generics but superior results)
Pricing Comparison (USD)
| Brand | Formulation | Dosage | Price per Unit |
|---|---|---|---|
| Caverject | Injection | 20 mcg | $35–$50 |
| MUSE | Urethral pellet | 500 mcg | $40–$60 |
| Vitaros | Topical cream | 300 mcg/g | $50–$70 |
| Generic | Injection | 10 mcg | $20–$30 |
(Prices vary by pharmacy and insurance coverage.)
Customer Testimonials
Dr. James K., Urologist (★★★★★)
“Alprostadil injections are my go-to for refractory ED. Patients report >80% satisfaction, even after failed oral therapy.”
Mark T., Patient (★★★★☆)
“MUSE pellets worked in 20 minutes. Slight burning, but far better than Viagra for my diabetes-related ED.”
Sarah L., Pharmacist (★★★★★)
“Demand for Vitaros cream is rising due to non-invasive application. Stock it regularly!”
Conclusion: Why Choose Alprostadil?
Alprostadil is a clinically validated, fast-acting solution for erectile dysfunction and vascular conditions. Its multiple formulations cater to individual preferences, while its high success rate makes it indispensable in urology and cardiology.
For optimal results, consult a physician to determine the best delivery method and dosage. Order today and experience unmatched efficacy in restoring sexual health and circulation!
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