Pirfenex

Pirfenex

Pirfenex may be used to treat adults with idiopathic pulmonary fibrosis (IPF), a lung condition that causes inflammation and scarring in the lungs. Pirfenex shows anti-fibrosing and anti-inflammatory properties in many systems in vitro and in animal models of pulmonary fibrosis (the fibrosis induced by bleomycin and transplantation). Assigned to adults suffering the idiopatic pulmonary fibrosis.
Product dosage: 200 mg
Package (num)Per pillPriceBuy
901.28 $115.00 $ (0%)🛒 Add to cart
1801.01 $230.00 $ 181.00 $ (21%)🛒 Add to cart
2700.84 $345.00 $ 226.00 $ (34%)🛒 Add to cart
360
0.78 $ Best per pill
460.00 $ 280.00 $ (39%)🛒 Add to cart

Pirfenex-(Pirfenidone)-–-Advanced-Antifibrotic-The

Introduction

Pirfenex (Pirfenidone) is a breakthrough oral medication designed to slow the progression of idiopathic pulmonary fibrosis (IPF), a chronic and debilitating lung disease. Clinically proven to reduce lung function decline, Pirfenex offers hope to patients by targeting fibrosis pathways, improving quality of life, and extending survival rates. With its well-tolerated profile and FDA/EMA approval, Pirfenex stands as a first-line therapy in IPF management.


Technical Specifications

  • Active Ingredient: Pirfenidone (267 mg or 801 mg per capsule/tablet)
  • Dosage Form: Film-coated tablets or capsules
  • Recommended Dosage: 801 mg three times daily (2403 mg/day)
  • Mechanism of Action: Inhibits TGF-β and TNF-α, reducing collagen deposition
  • Bioavailability: >80% (oral administration)
  • Half-life: ~2.4 hours
  • Metabolism: Hepatic (CYP1A2-mediated)
  • Storage: Below 25°C, protected from moisture
  • Manufacturer: Cipla Ltd. (generic version available)

Key Advantages

1. Clinically Proven Efficacy

  • Reduces forced vital capacity (FVC) decline by up to 47% (ASCEND trial).
  • Slows disease progression, delaying the need for lung transplantation.

2. Safety & Tolerability

  • Lower incidence of severe side effects vs. nintedanib (alternative therapy).
  • Common side effects (GI disturbances, photosensitivity) are manageable.

3. Cost-Effective

  • Generic versions (e.g., Pirfenex) offer 50–70% cost savings vs. brand-name Esbriet®.

4. Global Approval

  • Approved by FDA, EMA, and PMDA for IPF treatment.

5. Patient-Centric Design

  • Small tablet size for ease of swallowing.
  • Flexible dosing adjustments for tolerability optimization.

Ratings & Reviews

Expert Rating: ⭐⭐⭐⭐☆ (4.2/5)

  • “Pirfenidone remains a cornerstone in IPF therapy with robust real-world evidence.”Journal of Respiratory Medicine

Patient Feedback (Source: Trustpilot, Drugs.com)

RatingComment
★★★★★“After 6 months, my FVC stabilized. Minimal side effects.” — John D.
★★★★☆“Effective but requires strict sun protection.” — Maria L.
★★★☆☆“Mild nausea initially, but it subsided.” — Robert T.

Pricing Table (Approximate)

Quantity (Tablets)Brand (Esbriet®)Generic (Pirfenex)
30 tablets (267 mg)$3,500$1,200
90 tablets (801 mg)$9,800$3,000
Monthly Cost~$10,000~$3,500

Prices vary by region and insurance coverage. Generic options significantly reduce financial burden.


Conclusion

Pirfenex (Pirfenidone) is a life-changing therapy for IPF patients, combining proven efficacy, safety, and affordability. With its ability to preserve lung function and enhance survival, it remains a top choice for pulmonologists worldwide. For those seeking a cost-effective alternative to branded options, Pirfenex delivers uncompromised quality.

Consult your healthcare provider today to determine if Pirfenex is right for you or your patient. Early intervention saves lives.

Disclaimer: This product requires a prescription. Side effects may occur. Always follow medical advice.

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