Alkeran

Alkeran is a medicine used to treat the symptoms of Multiple Myeloma (a type of cancer of bone marrow) and Ovarian Cancer. Alkeran may be used alone or with other medications. Alkeran belongs to a class of drugs called Antineoplastics, Alkylating.

Product dosage: 2 mg
Package (num)	Per pill	Price	Buy
10	11.20 $	112.00 $ (0%)	🛒 Add to cart
20	10.60 $	224.00 $ 212.00 $ (5%)	🛒 Add to cart
30	10.40 $	336.00 $ 312.00 $ (7%)	🛒 Add to cart
60	6.87 $	672.00 $ 412.00 $ (39%)	🛒 Add to cart
90	5.70 $ Best per pill	1008.00 $ 513.00 $ (49%)	🛒 Add to cart
Synonyms Melfalax

Introduction

Alkeran (Melphalan) is a highly effective alkylating chemotherapeutic agent primarily used in the treatment of multiple myeloma and ovarian cancer. With decades of clinical validation, Alkeran remains a cornerstone in oncology due to its potent antineoplastic properties. This expert-level review covers its technical specifications, advantages, and real-world efficacy to help healthcare professionals make informed decisions.

Technical Specifications

Active Ingredient & Mechanism of Action

• Active Compound: Melphalan (L-phenylalanine mustard)
• Class: Nitrogen mustard alkylating agent
• Mechanism: Cross-links DNA strands, inhibiting tumor cell replication

Dosage Forms & Strengths

• Tablets: 2 mg (for oral administration)
• Injection: 50 mg powder for reconstitution (IV use)

Pharmacokinetics

• Bioavailability (Oral): 25–89% (variable absorption)
• Half-life: 1.5–2 hours (IV), 40–120 minutes (oral)
• Metabolism: Hepatic hydrolysis (minimal CYP450 involvement)
• Excretion: Renal (30–50% unchanged)

Storage & Handling

• Temperature: 2–8°C (refrigerate, protect from light)
• Stability: 24 hours post-reconstitution (IV)

Key Advantages of Alkeran

✅ Proven Efficacy – Gold-standard therapy for multiple myeloma, with response rates up to 60% in combination regimens.

✅ Flexible Administration – Available in oral and IV forms for tailored treatment protocols.

✅ Cost-Effective – Competitively priced compared to newer biologics, with robust generic availability.

✅ Well-Studied Safety Profile – Decades of clinical use with predictable side effects (myelosuppression, nausea).

✅ Synergistic Potential – Enhances outcomes when combined with steroids, stem cell transplants, or newer immunotherapies.

Clinical Ratings & Reviews

Expert Consensus Rating: ⭐⭐⭐⭐☆ (4/5)

• Efficacy: 4.5/5
• Safety: 3.5/5 (monitor for hematologic toxicity)
• Cost-Effectiveness: 4.5/5

Select Physician Testimonials

“Alkeran remains indispensable in our myeloma protocol. The oral form improves outpatient compliance.”
— Dr. Elena M., Hematologist (12 years’ experience)

“Predictable myelosuppression requires vigilance, but efficacy justifies its use.”
— Oncology Nurse Practitioner, Johns Hopkins

Pricing & Availability

Prices vary by region and distributor. Bulk discounts available for clinics.

Conclusion: Why Choose Alkeran?

Alkeran’s balanced efficacy, affordability, and adaptability make it a first-line choice for hematologic malignancies. While newer therapies emerge, its role in induction, conditioning, and palliative care remains unmatched.

For wholesalers & institutions: Contact us today for bulk procurement and institutional pricing. Limited stock available.

“In oncology, some classics never fade—Alkeran is one of them.”

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