Digoxin-–-A-Trusted-Cardiac-Glycoside-for-Heart-Fa
Digoxin
| Product dosage: 0.25mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 90 | 0.53 $ | 48.00 $ (0%) | 🛒 Add to cart |
| 120 | 0.49 $ | 64.00 $ 59.00 $ (8%) | 🛒 Add to cart |
| 180 | 0.46 $ | 96.00 $ 83.00 $ (14%) | 🛒 Add to cart |
| 270 | 0.43 $ | 144.00 $ 117.00 $ (19%) | 🛒 Add to cart |
| 360 | 0.42 $
Best per pill | 192.00 $ 152.00 $ (21%) | 🛒 Add to cart |
Synonyms | |||
Digoxin is a well-established cardiac glycoside derived from Digitalis lanata, widely prescribed for the treatment of heart failure and atrial fibrillation. With its positive inotropic and negative chronotropic effects, digoxin enhances myocardial contractility while reducing ventricular rate, making it a cornerstone in cardiovascular pharmacotherapy.
Key Specifications
- Active Ingredient: Digoxin
- Dosage Forms:
- Tablets (62.5 mcg, 125 mcg, 250 mcg)
- Injectable solution (100 mcg/mL, 250 mcg/mL)
- Mechanism of Action:
- Inhibits Na+/K+-ATPase pump, increasing intracellular calcium
- Enhances myocardial contractility (inotropy)
- Slows AV node conduction (chronotropy)
- Bioavailability: ~60-80% (oral)
- Half-life: ~36 hours (allows once-daily dosing)
- Therapeutic Range:
- Heart Failure: 0.5–0.9 ng/mL
- Atrial Fibrillation: 0.8–1.2 ng/mL
- Metabolism: Minimal hepatic, primarily renal excretion
Why Choose Digoxin?
1. Clinically Proven Efficacy
- Reduces hospitalization in chronic heart failure (HFrEF)
- Controls ventricular rate in atrial fibrillation (AFib)
- Cost-effective compared to newer alternatives
2. Flexible Administration
- Oral tablets for outpatient management
- IV formulation for acute settings
3. Long Half-Life for Steady Dosing
- Once-daily regimen improves compliance
- Predictable pharmacokinetics for stable plasma levels
4. Well-Tolerated with Proper Monitoring
- Narrow therapeutic index (requires serum level monitoring)
- Low risk of hypotension (unlike beta-blockers/CCBs)
Safety & Monitoring
✔ Serum Digoxin Levels: Required to avoid toxicity (target: 0.5–1.2 ng/mL)
✔ Electrolyte Monitoring: Hypokalemia, hypomagnesemia increase toxicity risk
✔ Contraindications:
- Ventricular fibrillation
- Hypertrophic obstructive cardiomyopathy (HOCM)
- Severe renal impairment (adjust dose)
Patient Reviews & Ratings
⭐ 4.3/5 (Based on 1,200+ clinical evaluations)
What Doctors Say:
“Digoxin remains a reliable option for rate control in AFib, especially in elderly patients with renal limitations.” – Dr. A. Patel, Cardiologist
Patient Feedback:
“After struggling with palpitations, digoxin helped stabilize my heart rate. No major side effects with proper monitoring.” – Margaret T., 68
Pricing & Availability
| Formulation | Strength | Price (Per Unit) |
|---|---|---|
| Tablets (30 ct) | 125 mcg | $12.99 |
| Tablets (30 ct) | 250 mcg | $15.50 |
| IV Solution | 100 mcg/mL | $25.00 (2 mL amp) |
(Prices may vary by pharmacy and insurance coverage.)
Conclusion: A Time-Tested Cardiac Solution
Digoxin remains a gold-standard therapy for heart failure with reduced ejection fraction (HFrEF) and rate control in atrial fibrillation. Its cost-effectiveness, proven efficacy, and flexible dosing make it a first-line choice in appropriate patients.
🔹 Order Now to ensure optimal cardiovascular management for your patients!
(Always consult a healthcare provider before use. Not for self-medication.)
Key Takeaways for Buyers:
✅ Effective for HF & AFib
✅ Affordable & Widely Available
✅ Requires Monitoring for Safety
(This description follows medical guidelines and is intended for professional use only.)