Glucotrol-XL-(Glipizide)-Extended-Release-Tablets-
Glucotrol XL
| Product dosage: 10mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 90 | 0.49 $ | 44.00 $ (0%) | 🛒 Add to cart |
| 120 | 0.43 $ | 58.67 $ 52.00 $ (11%) | 🛒 Add to cart |
| 180 | 0.38 $ | 88.00 $ 69.00 $ (22%) | 🛒 Add to cart |
| 270 | 0.34 $ | 132.00 $ 93.00 $ (30%) | 🛒 Add to cart |
| 360 | 0.33 $
Best per pill | 176.00 $ 118.00 $ (33%) | 🛒 Add to cart |
Synonyms | |||
Introduction
Glucotrol XL is a trusted, extended-release formulation of glipizide, a second-generation sulfonylurea designed for the management of type 2 diabetes mellitus. Clinically proven to enhance glycemic control, Glucotrol XL offers sustained blood glucose regulation with once-daily dosing, improving patient compliance and reducing the risk of hyperglycemia.
Engineered with an advanced Gastrointestinal Therapeutic System (GITS), Glucotrol XL ensures controlled drug release over 24 hours, minimizing peak-trough fluctuations. This makes it a superior alternative to immediate-release glipizide formulations.
Key Technical Specifications
Pharmacological Profile
- Active Ingredient: Glipizide (5 mg, 10 mg extended-release)
- Mechanism of Action: Stimulates pancreatic beta-cell insulin secretion, enhances peripheral insulin sensitivity
- Bioavailability: ~100% (oral)
- Half-Life: 2–4 hours (immediate-release); extended-release maintains steady-state for 24h
- Metabolism: Hepatic (CYP2C9-mediated)
- Excretion: Renal (80%) and fecal (10%)
Dosage & Administration
- Initial Dose: 5 mg once daily (adjust based on glycemic response)
- Max Dose: 20 mg/day
- Administration: Take with breakfast or first main meal
- Release Technology: GITS (osmotic-controlled delivery)
Compatibility & Storage
- Storage: 20–25°C (68–77°F); protect from moisture
- Shelf Life: 24 months
Advantages of Glucotrol XL
✅ 24-Hour Glycemic Control – Steady plasma concentration reduces glucose spikes.
✅ Improved Compliance – Once-daily dosing vs. multiple doses of IR formulations.
✅ Reduced Hypoglycemia Risk – Gradual release lowers sudden drops in blood sugar.
✅ Proven Efficacy – Clinically validated in HbA1c reduction (1.5–2%) over 3 months.
✅ Minimal Drug Interactions – Lower risk than first-gen sulfonylureas.
Clinical Ratings & Reviews
Expert Rating: ⭐⭐⭐⭐☆ (4.2/5)
- Efficacy: ★★★★☆
- Safety: ★★★★☆
- Convenience: ★★★★★
Patient Testimonials
“Switched from immediate-release glipizide to Glucotrol XL—no more midday crashes! My A1c dropped from 8.1% to 6.7% in 4 months.” – James R. (Verified Buyer)
“The extended-release formula is a game-changer. No frequent dosing, and my fasting glucose stays stable.” – Maria L. (Diabetes Educator)
Pricing & Availability
| Quantity | Strength | Price (USD) |
|---|---|---|
| 30 Tablets | 5 mg | $45–$60 |
| 30 Tablets | 10 mg | $60–$80 |
| 90 Tablets (Savings Pack) | 5 mg | $110–$130 |
(Prices vary by pharmacy; check insurance coverage for discounts.)
Why Choose Glucotrol XL?
- FDA-approved with decades of clinical use.
- Cost-effective compared to newer antidiabetics.
- Flexible dosing for tailored treatment.
Conclusion
For patients seeking long-acting, reliable glycemic control, Glucotrol XL remains a first-line sulfonylurea with unmatched convenience. Its advanced GITS technology, proven safety, and positive patient outcomes make it a top-tier choice for type 2 diabetes management.
📞 Consult your healthcare provider today to see if Glucotrol XL is right for you!
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