Hydrochlorothiazide-(HCTZ)-–-Premium-Diuretic-for-
Hydrochlorothiazide
Hydrochlorothiazide (HCTZ) is a first-line thiazide diuretic clinically proven to treat hypertension (high blood pressure) and edema associated with congestive heart failure, renal disorders, and liver cirrhosis. With a well-established safety profile and rapid onset of action, HCTZ is a trusted choice among healthcare professionals for effective fluid balance regulation and blood pressure control.
Technical Specifications
- Active Ingredient: Hydrochlorothiazide
- Dosage Forms:
- Tablets: 12.5 mg, 25 mg, 50 mg
- Oral suspension (compounded)
- Mechanism of Action: Inhibits sodium-chloride symporter in distal convoluted tubule → promotes diuresis
- Onset of Action: 2 hours (peak effect: 4–6 hours)
- Duration: 6–12 hours
- Bioavailability: ~70%
- Metabolism: Minimal hepatic metabolism (renal excretion)
- Half-Life: 5.6–14.8 hours
- Compatibility: Often combined with ACE inhibitors, ARBs, or beta-blockers for synergistic effects
Key Advantages of Hydrochlorothiazide
✅ Proven Efficacy – Clinically validated to reduce systolic/diastolic BP by 10–15 mmHg.
✅ Cost-Effective – Generic availability ensures affordability without compromising quality.
✅ Versatile Application – Effective for hypertension, edema, and nephrolithiasis (calcium-based stones).
✅ Minimal Drug Interactions – Low risk of pharmacokinetic interference with most medications.
✅ Well-Tolerated – Suitable for long-term use with routine monitoring.
Performance Rating
⭐ 4.7/5 (Based on 1,200+ Clinical Reviews)
- Effectiveness: ★★★★☆
- Safety: ★★★★☆
- Value for Money: ★★★★★
- Patient Compliance: ★★★★☆
Pricing Table (Generic HCTZ)
| Dosage (mg) | Quantity | Price (USD) | Savings |
|---|---|---|---|
| 12.5 | 30 tabs | $8.99 | 10% off |
| 25 | 90 tabs | $15.50 | 20% off |
| 50 | 100 tabs | $22.75 | 25% off |
Branded versions (e.g., Microzide®) may cost 2–3x more.
Customer Testimonials
Dr. Emily R., Cardiologist (★★★★★)
“Hydrochlorothiazide remains my go-to for stage 1–2 hypertension. Patients report fewer side effects compared to loop diuretics, and adherence rates are excellent.”
James L. (Patient, ★★★★☆)
“Within a week, my swelling reduced significantly. Mild dizziness initially, but it subsided. Great value!”
Clinic Feedback (Aggregate Score: 4.6/5)
- 89% reported “noticeable BP reduction” within 14 days.
- 7% experienced mild hypokalemia (managed with supplements).
Why Choose Hydrochlorothiazide?
- Gold Standard Therapy – Recommended by JNC 8 and ESC guidelines.
- Rapid Results – Measurable effects within days.
- Flexible Dosing – Adjustable for renal/hepatic impairment.
- Combo Potential – Enhances efficacy of RAS inhibitors.
Conclusion
Hydrochlorothiazide delivers unmatched value as a potent, low-cost diuretic with decades of clinical validation. Whether for hypertension or edema, its predictable pharmacokinetics and tolerability make it a staple in modern pharmacotherapy.
Order today and experience the benchmark in diuretic care!
Disclaimer: Consult a healthcare provider before use. Not for patients with sulfonamide allergy or anuria.
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