Isordil-(Isosorbide-Dinitrate)-–-Expert-Medical-Ov

Isordil

Isordil

Isordil is used for preventing symptoms of angina (chest pain) caused by heart disease. This medicine is used alone or with other medicines. This medicine is NOT intended for the immediate relief of acute attacks of angina.
Product dosage: 10mg
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Product dosage: 5mg
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360
0.35 $ Best per pill
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Introduction

Isordil (Isosorbide Dinitrate) is a highly effective nitrate vasodilator prescribed for the prevention and treatment of angina pectoris (chest pain caused by coronary artery disease). By relaxing blood vessels, Isordil improves oxygen supply to the heart, reducing cardiac workload. Trusted by cardiologists worldwide, Isordil offers rapid relief and long-term cardiovascular support.


Key Specifications

Active Ingredient & Mechanism of Action

  • Active Compound: Isosorbide Dinitrate
  • Class: Organic nitrate vasodilator
  • Mechanism: Converts to nitric oxide (NO), dilating veins and arteries to reduce cardiac preload and afterload.

Dosage Forms & Strengths

  • Tablets: 5 mg, 10 mg, 20 mg, 30 mg, 40 mg
  • Sublingual tablets: 2.5 mg, 5 mg (for rapid action)
  • Extended-release capsules: 40 mg, 60 mg

Pharmacokinetics

  • Onset of Action: 1–3 minutes (sublingual), 15–40 minutes (oral)
  • Duration: 2–6 hours (immediate-release), up to 12 hours (extended-release)
  • Metabolism: Hepatic (via denitration)
  • Half-life: ~1 hour (parent compound), 4 hours (active metabolites)

Storage & Handling

  • Storage: Keep in original container, away from moisture and light.
  • Stability: Avoid extreme temperatures (>30°C).

Advantages of Isordil

Fast-Acting Relief – Sublingual form provides rapid angina relief within minutes.
Proven Efficacy – Decades of clinical use with well-documented success in angina management.
Flexible Dosage Options – Available in immediate and extended-release forms for tailored therapy.
Cost-Effective – Generic versions offer affordability without compromising quality.
Minimal Side Effects – Well-tolerated when used as prescribed (headache may occur initially).


Clinical Ratings & Reviews

Expert Rating: ⭐⭐⭐⭐☆ (4.2/5)

  • Effectiveness: 4.5/5
  • Tolerability: 4.0/5
  • Convenience: 4.0/5

Patient Testimonials

“Isordil has been a lifesaver for my angina attacks. The sublingual tablets work within minutes!”James R. (Verified Buyer, ★★★★★)
“My cardiologist recommended Isordil, and it’s significantly improved my exercise tolerance.”Maria L. (★★★★☆)


Pricing Comparison

FormulationStrengthQuantityAvg. Price (USD)
Sublingual Tablets5 mg100 tabs$25–$40
Oral Tablets20 mg90 tabs$30–$50
Extended-Release40 mg30 caps$45–$70

(Prices may vary by pharmacy and insurance coverage.)


Safety & Precautions

Contraindications:

  • Concomitant use with PDE-5 inhibitors (e.g., sildenafil) due to severe hypotension risk.
  • Severe anemia or intracranial pressure concerns.

Side Effects (Rare but Possible):

  • Headache (most common, usually transient).
  • Dizziness, hypotension, or flushing.

💡 Pro Tip: To avoid tolerance, follow a nitrate-free interval (e.g., 10–12 hours overnight).


Conclusion: Why Choose Isordil?

Isordil remains a gold-standard antianginal medication, combining fast action, reliability, and affordability. Whether for acute relief or long-term management, its flexible dosing and proven track record make it a top choice for patients and physicians alike.

📞 Consult your healthcare provider today to see if Isordil is right for you!

Key Takeaways for Buyers:

  • Immediate & extended-release options for customized treatment.
  • High patient satisfaction with rapid symptom relief.
  • Competitive pricing across formulations.

(Note: Always follow medical advice; this is not a substitute for professional consultation.)