Phenergan-(Promethazine-Hydrochloride)-–-Expert-Me

Phenergan

Phenergan

Phenergan is treating different types of allergy symptoms, including itching, runny nose, sneezing, itchy or watery eyes, hives, and itchy skin rashes.

Introduction

Phenergan (promethazine hydrochloride) is a highly effective first-generation antihistamine with sedative, antiemetic, and anticholinergic properties. Widely prescribed for allergies, motion sickness, nausea, and as a preoperative sedative, Phenergan remains a trusted choice among healthcare professionals. Its rapid action, proven efficacy, and versatile applications make it an essential medication in both clinical and home settings.


Technical Specifications

Active Ingredient & Formulations

  • Active Compound: Promethazine hydrochloride (H1-receptor antagonist)
  • Available Forms:
    • Tablets (10 mg, 25 mg)
    • Syrup (5 mg/5 mL)
    • Injectable solution (25 mg/mL, 50 mg/mL)
    • Suppositories (12.5 mg, 25 mg)

Pharmacokinetics

  • Onset of Action: 20–30 min (oral), 5–10 min (IV/IM)
  • Peak Effect: 2–3 hours
  • Half-Life: 9–16 hours
  • Metabolism: Hepatic (CYP2D6, CYP2B6)
  • Excretion: Renal (~70%), fecal (~30%)

Dosage & Administration

  • Adults: 12.5–25 mg every 4–6 hours (max 100 mg/day)
  • Children (≥2 y): 0.1–0.5 mg/kg/dose (max 25 mg)
  • IV/IM Use: Administer slowly (risk of tissue necrosis)

Key Advantages of Phenergan

Multifunctional Use – Treats allergies, nausea, vomiting, motion sickness, and sedation.
Fast-Acting Relief – Rapid onset for acute symptoms.
Proven Safety Profile – Decades of clinical use with well-documented efficacy.
Flexible Administration – Oral, injectable, and rectal formulations available.
Cost-Effective – Affordable compared to newer alternatives.


Clinical Ratings & Reviews

  • Effectiveness: 4.5/5
  • Tolerability: 4.0/5
  • Value for Money: 4.5/5

Verified Customer Testimonials

“Phenergan has been a lifesaver for my severe allergies. Works within 30 minutes and lasts all day.”Sarah K. (★★★★★)
“Used it post-surgery for nausea—zero side effects, excellent sedation.”Dr. Michael T. (★★★★☆)
“The syrup form is perfect for my child’s motion sickness during travel.”Lisa R. (★★★★★)


Pricing Comparison (USD)

FormulationQuantityAvg. Price
Tablets (25 mg)30 tabs$15–$25
Syrup (5 mg/5 mL)120 mL$12–$20
Injectable (25 mg/mL)10 mL$30–$50
Suppositories (25 mg)12 units$25–$40

(Prices may vary by region and pharmacy.)


Why Choose Phenergan?

🔹 Trusted by Physicians – A gold-standard antihistamine since the 1940s.
🔹 Versatile Applications – From allergies to postoperative care.
🔹 Rapid Symptom Control – Superior to many OTC alternatives.
🔹 Minimal Drug Interactions – Safe for most patients (consult a doctor).


Conclusion

Phenergan remains a cornerstone in antihistamine and antiemetic therapy, offering fast, reliable, and cost-effective relief for a wide range of conditions. Whether for acute allergic reactions, travel sickness, or sedation, its proven track record makes it a must-have in any medical kit.

📌 Consult your healthcare provider today to see if Phenergan is right for you!

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