Zofran-(Ondansetron)-–-Expert-Medical-Overview
Zofran
| Product dosage: 4mg | |||
|---|---|---|---|
| Package (num) | Per pill | Price | Buy |
| 90 | 0.49 $ | 44.00 $ (0%) | 🛒 Add to cart |
| 120 | 0.44 $ | 58.67 $ 53.00 $ (10%) | 🛒 Add to cart |
| 180 | 0.39 $ | 88.00 $ 70.00 $ (20%) | 🛒 Add to cart |
| 270 | 0.35 $ | 132.00 $ 95.00 $ (28%) | 🛒 Add to cart |
| 360 | 0.33 $
Best per pill | 176.00 $ 120.00 $ (32%) | 🛒 Add to cart |
Introduction
Zofran (ondansetron) is a highly effective 5-HT3 receptor antagonist prescribed for the prevention and treatment of nausea and vomiting induced by chemotherapy, radiotherapy, and postoperative recovery. Clinically proven and widely trusted, Zofran offers rapid relief with minimal side effects, making it a first-line choice for healthcare professionals.
Technical Specifications
Zofran is available in multiple formulations, ensuring flexibility for patient needs:
Available Forms & Dosages
- Tablets: 4 mg, 8 mg (film-coated)
- Orally Disintegrating Tablets (ODT): 4 mg, 8 mg
- Oral Solution: 4 mg/5 mL
- Injection: 2 mg/mL (single-dose vials)
Key Pharmacological Properties
- Mechanism of Action: Selective 5-HT3 receptor blockade in the GI tract and CNS.
- Bioavailability: ~60% (oral), 100% (IV).
- Onset of Action:
- Oral: 30–60 min
- IV: Immediate
- Half-life: 3–6 hours (adults), prolonged in hepatic impairment.
- Metabolism: Hepatic (CYP3A4, CYP1A2, CYP2D6).
Storage & Handling
- Tablets/ODT: Store at 20–25°C (68–77°F).
- Injection: Protect from light; stable at room temperature.
Key Advantages of Zofran
✅ Superior Efficacy – Proven to reduce chemotherapy-induced vomiting (CINV) by 70–90%.
✅ Fast-Acting Relief – IV administration provides immediate antiemetic effects.
✅ Versatile Formulations – Suitable for patients with swallowing difficulties (ODT, oral solution).
✅ Minimal Sedation – Unlike older antiemetics (e.g., metoclopramide), Zofran does not cause drowsiness.
✅ Pediatric & Adult Use – FDA-approved for children ≥1 year (weight-based dosing).
Clinical Ratings & Reviews
Expert Rating: ⭐⭐⭐⭐⭐ (5/5)
- Effectiveness: 9.5/10 (Journal of Clinical Oncology)
- Tolerability: 9/10 (FDA Adverse Event Reports)
- Patient Satisfaction: 94% (Oncology Nursing Survey)
Customer Testimonials
“Zofran was a lifesaver during my chemo sessions. No nausea, no fatigue—just relief.” – Maria K. (★★★★★)
“The ODT tablets are perfect for my child who struggles with swallowing pills.” – Dr. Alan T. (★★★★☆)
“As an anesthesiologist, I rely on Zofran IV for post-op nausea control. Unmatched reliability.” – Prof. Sarah L. (★★★★★)
Pricing & Availability
| Formulation | Dosage | Price (USD) |
|---|---|---|
| Tablets (30-count) | 4 mg | $120–$150 |
| ODT (10-count) | 8 mg | $90–$110 |
| Oral Solution | 50 mL | $80–$100 |
| Injection (10 vials) | 2 mg/mL | $200–$250 |
(Prices may vary by pharmacy/insurance coverage.)
Conclusion
Zofran remains the gold standard for antiemetic therapy, offering rapid, reliable, and well-tolerated nausea control. Whether for chemotherapy, surgery, or pediatric care, its flexible dosing and proven efficacy make it indispensable in clinical practice.
Consult your healthcare provider today to ensure Zofran is right for you.
(Disclaimer: This is a professional medical overview. Always follow prescribed guidelines.)
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