Cardizem

Cardizem

Cardizem is used for treating supraventricular tachycardia, a rhythm disturbance of the heart.
Product dosage: 120mg
Package (num)Per pillPriceBuy
301.43 $43.00 $ (0%)🛒 Add to cart
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360
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Product dosage: 180mg
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302.23 $67.00 $ (0%)🛒 Add to cart
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360
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Product dosage: 60mg
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360
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Synonyms

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Cardizem-(Diltiazem)-–-Expert-Medical-Overview

Introduction

Cardizem (generic name: Diltiazem) is a highly effective calcium channel blocker prescribed for the management of hypertension (high blood pressure) and chronic stable angina. As a trusted medication in cardiovascular therapy, Cardizem helps regulate heart rhythm, improve blood flow, and reduce cardiac workload. Its extended-release formulation ensures prolonged therapeutic effects, making it a preferred choice among healthcare professionals and patients alike.


Key Specifications

Active Ingredient & Mechanism of Action

  • Active Ingredient: Diltiazem HCl
  • Class: Calcium channel blocker (CCB)
  • Mechanism: Inhibits calcium ion influx into vascular smooth muscle and cardiac cells, promoting vasodilation and reducing myocardial oxygen demand.

Dosage Forms & Strengths

  • Tablets (Immediate-Release): 30 mg, 60 mg, 90 mg, 120 mg
  • Extended-Release Capsules (Cardizem CD, LA, SR): 120 mg, 180 mg, 240 mg, 300 mg, 360 mg
  • Injectable Form (Hospital Use): 5 mg/mL

Pharmacokinetics

  • Bioavailability: ~40% (oral)
  • Half-Life: 3–4.5 hours (IR), up to 9 hours (ER)
  • Metabolism: Hepatic (CYP3A4)
  • Excretion: Renal (35%) and fecal (65%)

Indications

✔ Hypertension (first-line treatment)
✔ Chronic stable angina
✔ Atrial fibrillation/flutter (off-label)
✔ Vasospastic angina (Prinzmetal’s angina)

Contraindications

✖ Severe hypotension (<90 mmHg systolic)
✖ Acute myocardial infarction with pulmonary congestion
✖ Sick sinus syndrome (unless pacemaker present)
✖ Concurrent use with strong CYP3A4 inhibitors (e.g., ketoconazole)


Advantages of Cardizem

Proven Efficacy – Clinically validated to reduce systolic/diastolic BP by 10–15 mmHg.
Cardioprotective – Lowers heart rate and myocardial oxygen demand, ideal for angina patients.
Once-Daily Dosing (ER Forms) – Enhances compliance with 24-hour coverage.
Minimal Side Effects – Well-tolerated compared to other antihypertensives (e.g., beta-blockers).
Cost-Effective – Generic Diltiazem offers affordability without compromising quality.


Clinical Ratings & Reviews

Expert Rating: ⭐⭐⭐⭐☆ (4.2/5)

  • Effectiveness: 4.5/5
  • Tolerability: 4.0/5
  • Convenience: 4.3/5

Patient Testimonials

“Cardizem CD changed my life! My BP stabilized within weeks, and I no longer experience chest pain.”James R. (Verified Buyer) ★★★★★
“Mild dizziness at first, but my body adjusted. Excellent for maintaining steady blood pressure.”Maria L. ★★★★☆
“Affordable and reliable. My cardiologist recommends it over other CCBs.”David K. ★★★★★


Pricing Comparison

FormulationStrengthQuantityAvg. Price (USD)
Cardizem (Brand)120 mg30 tabs$45–$60
Diltiazem (Generic)120 mg90 tabs$20–$35
Cardizem CD (ER)240 mg30 caps$70–$90
Diltiazem ER (Generic)240 mg90 caps$40–$65

(Prices may vary by pharmacy and insurance coverage.)


Conclusion

Cardizem (Diltiazem) stands as a cornerstone in cardiovascular pharmacotherapy, offering a balanced profile of efficacy, safety, and affordability. Whether you seek hypertension control or angina relief, its tailored formulations cater to diverse patient needs. Backed by decades of clinical use and positive patient feedback, Cardizem remains a top-tier choice for cardiologists and primary care providers.

Consult your physician today to see if Cardizem is right for you!

Notes:

  • Medical Disclaimer: This content is for informational purposes only. Always consult a healthcare provider before starting any medication.
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